Cargando…
Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines
Standard treatment of poisoning by organophosphorus anticholinesterases uses atropine to reduce the muscarinic effects of acetylcholine accumulation and oximes to reactivate acetylcholinesterase (the effectiveness of which depends on the specific anticholinesterase), but does not directly address th...
Autores principales: | Ring, Avi, Strom, Bjorn Oddvar, Turner, Simon R., Timperley, Christopher M., Bird, Michael, Green, A. Christopher, Chad, John E., Worek, Franz, Tattersall, John E. H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537131/ https://www.ncbi.nlm.nih.gov/pubmed/26274808 http://dx.doi.org/10.1371/journal.pone.0135811 |
Ejemplares similares
-
Modelling organophosphate intoxication in C. elegans highlights nicotinic acetylcholine receptor determinants that mitigate poisoning
por: Izquierdo, Patricia G., et al.
Publicado: (2023) -
Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice
por: Kassa, Jiri, et al.
Publicado: (2022) -
Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine
por: Schapira, Matthieu, et al.
Publicado: (2002) -
Cytotoxicity-related Effects of Imidazolium and Chlorinated Bispyridinium Oximes in SH-SY5Y Cells
por: Zandona, Antonio, et al.
Publicado: (2023) -
Alcohol’s Actions on Neuronal Nicotinic Acetylcholine Receptors
por: Davis, Tiffany J., et al.
Publicado: (2006)