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The Accumulation of VEGFA in the Glomerular Basement Membrane and Its Relationship with Podocyte Injury and Proteinuria in Alport Syndrome

The pathogenesis of proteinuria in Alport syndrome (AS) remains unclear. Vascular endothelial growth factor A (VEGFA) is a key regulator of the glomerular filtration barrier (GFB). This study explored the expression of VEGFA in the glomeruli and its accumulation in the glomerular basement membrane (...

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Detalles Bibliográficos
Autores principales: Wang, Haiyan, Yue, Zhihui, Wu, Jinlang, Liu, Ting, Mo, Ying, Jiang, Xiaoyun, Sun, Liangzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537134/
https://www.ncbi.nlm.nih.gov/pubmed/26274923
http://dx.doi.org/10.1371/journal.pone.0135648