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Free Fatty Acid Effects on the Atrial Myocardium: Membrane Ionic Currents Are Remodeled by the Disruption of T-Tubular Architecture

BACKGROUND: Epicardial adiposity and plasma levels of free fatty acids (FFAs) are elevated in atrial fibrillation, heart failure and obesity, with potentially detrimental effects on myocardial function. As major components of epicardial fat, FFAs may be abnormally regulated, with a potential to detr...

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Detalles Bibliográficos
Autores principales: O’Connell, Ryan P., Musa, Hassan, Gomez, Mario San Martin, Avula, Uma Mahesh, Herron, Todd J., Kalifa, Jerome, Anumonwo, Justus M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537212/
https://www.ncbi.nlm.nih.gov/pubmed/26274906
http://dx.doi.org/10.1371/journal.pone.0133052