Absence of Vitamin K-Dependent γ-Carboxylation in Human Periostin Extracted from Fibrotic Lung or Secreted from a Cell Line Engineered to Optimize γ-Carboxylation

Periostin (PN, gene name POSTN) is an extracellular matrix protein that is up-regulated in bronchial epithelial cells and lung fibroblasts by TH-2 cytokines. Its paralog, TGF-β-induced protein (βig-h3, gene name TGFBI), is also expressed in the lung and up-regulated in bronchial myofibroblasts by TG...

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Detalles Bibliográficos
Autores principales: Annis, Douglas S., Ma, Hanqing, Balas, Danika M., Kumfer, Kraig T., Sandbo, Nathan, Potts, Gregory K., Coon, Joshua J., Mosher, Deane F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537219/
https://www.ncbi.nlm.nih.gov/pubmed/26273833
http://dx.doi.org/10.1371/journal.pone.0135374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537219/
https://www.ncbi.nlm.nih.gov/pubmed/26273833
http://dx.doi.org/10.1371/journal.pone.0135374

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