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Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle Regeneration

Following myonecrosis, muscle satellite cells proliferate, differentiate and fuse, creating new myofibers. The Runx1 transcription factor is not expressed in naïve developing muscle or in adult muscle tissue. However, it is highly expressed in muscles exposed to myopathic damage yet, the role of Run...

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Detalles Bibliográficos
Autores principales: Umansky, Kfir Baruch, Gruenbaum-Cohen, Yael, Tsoory, Michael, Feldmesser, Ester, Goldenberg, Dalia, Brenner, Ori, Groner, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537234/
https://www.ncbi.nlm.nih.gov/pubmed/26275053
http://dx.doi.org/10.1371/journal.pgen.1005457