IQGAP1 and IQGAP3 serve individually essential roles in normal epidermal homeostasis and tumor progression

IQGAP scaffolding proteins regulate many essential cellular processes including growth factor receptor signaling, cytoskeletal rearrangement, adhesion and proliferation, and are highly expressed in many cancers. Using genetically engineered human skin tissue in vivo, we demonstrate that diminished,...

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Detalles Bibliográficos
Autores principales: Monteleon, Christine L., McNeal, Andrew, Duperret, Elizabeth K., Oh, Seung Ja, Schapira, Emily, Ridky, Todd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537348/
https://www.ncbi.nlm.nih.gov/pubmed/25848980
http://dx.doi.org/10.1038/jid.2015.140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537348/
https://www.ncbi.nlm.nih.gov/pubmed/25848980
http://dx.doi.org/10.1038/jid.2015.140

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