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Epigenetic Silencing of SPINT2 promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma

Aberrant HGF-MET signaling activation via interactions with surrounding stromal cells in tumor microenvironment plays significant roles in malignant tumor progression. However, extracellular proteolytic regulation of HGF activation which is influenced by the tumor microenvironment and its consequent...

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Detalles Bibliográficos
Autores principales: Hwang, Soonyean, Kim, Hye-Eun, Min, Michelle, Raghunathan, Rekha, Panova, Izabela P., Munshi, Ruchi, Ryu, Byungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537358/
https://www.ncbi.nlm.nih.gov/pubmed/25910030
http://dx.doi.org/10.1038/jid.2015.160