Cargando…

Epigenetic Silencing of SPINT2 promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma

Aberrant HGF-MET signaling activation via interactions with surrounding stromal cells in tumor microenvironment plays significant roles in malignant tumor progression. However, extracellular proteolytic regulation of HGF activation which is influenced by the tumor microenvironment and its consequent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hwang, Soonyean, Kim, Hye-Eun, Min, Michelle, Raghunathan, Rekha, Panova, Izabela P., Munshi, Ruchi, Ryu, Byungwoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537358/ https://www.ncbi.nlm.nih.gov/pubmed/25910030 http://dx.doi.org/10.1038/jid.2015.160

Ejemplares similares

Notch3 Signaling-Mediated Melanoma-Endothelial Crosstalk Regulates Melanoma Stem-Like Cell Homeostasis and Niche Morphogenesis
por: Hsu, Mei-Yu, et al.
Publicado: (2017)

HGF/c-MET Signaling in Melanocytes and Melanoma
por: Czyz, Malgorzata
Publicado: (2018)

The Role of HGF/MET Signaling in Metastatic Uveal Melanoma
por: Tanaka, Ryota, et al.
Publicado: (2021)

Aberrant methylation and silencing of the SPINT2 gene in high‐grade gliomas
por: Fukushima, Tsuyoshi, et al.
Publicado: (2018)

Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion
por: Cao, Hui-Hui, et al.
Publicado: (2015)

Epigenetic Upregulation of HGF and c-Met Drives Metastasis in Hepatocellular Carcinoma
por: Ogunwobi, Olorunseun O., et al.
Publicado: (2013)

Role of the HGF/c-MET tyrosine kinase inhibitors in metastasic melanoma
por: Demkova, Lucia, et al.
Publicado: (2018)

Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility
por: Li, Ran, et al.
Publicado: (2015)

Cyclic Peptide-Based Biologics Regulating HGF-MET
por: Sato, Hiroki, et al.
Publicado: (2020)

The Interplay between HGF/c-met Axis and Nox4 in BRAF Mutated Melanoma
por: Beretti, Francesca, et al.
Publicado: (2021)

HGF-MET as a breast cancer biomarker
por: Liu, Shuying
Publicado: (2015)

HGF–Met Pathway in Regeneration and Drug Discovery
por: Matsumoto, Kunio, et al.
Publicado: (2014)

HGF/Met Axis in Heart Function and Cardioprotection
por: Gallo, Simona, et al.
Publicado: (2014)

Physiological Signaling and Structure of the HGF Receptor MET
por: Baldanzi, Gianluca, et al.
Publicado: (2014)

HGF/MET Signaling in Malignant Brain Tumors
por: Mulcahy, Elizabeth Qian Xu, et al.
Publicado: (2020)

Epigenetic regulation of HGF/Met receptor axis is critical for the outgrowth of bone metastasis from breast carcinoma
por: Bendinelli, Paola, et al.
Publicado: (2017)

Decreased expression of SPINT1-AS1 and SPINT1 mRNA might be independent unfavorable prognostic indicators in esophageal squamous cell carcinoma
por: Shen, Fang-Fang, et al.
Publicado: (2019)

HGF-independent Potentiation of EGFR Action by c-Met
por: Dulak, Austin M., et al.
Publicado: (2011)

Targeting the HGF-cMET Axis in Hepatocellular Carcinoma
por: Venepalli, Neeta K., et al.
Publicado: (2013)

The role of HGF/c-MET signaling pathway in lymphoma
por: Lam, Bao Quoc, et al.
Publicado: (2016)

HGF/MET and the Immune System: Relevance for Cancer Immunotherapy
por: Papaccio, Federica, et al.
Publicado: (2018)

Role and Therapeutic Targeting of the HGF/MET Pathway in Glioblastoma
por: Cruickshanks, Nichola, et al.
Publicado: (2017)

The Function of the HGF/c-Met Axis in Hepatocellular Carcinoma
por: Wang, Haiyu, et al.
Publicado: (2020)

Targeting HGF/c-MET Axis in Pancreatic Cancer
por: Pothula, Srinivasa P., et al.
Publicado: (2020)

HGF and MET: From Brain Development to Neurological Disorders
por: Desole, Claudia, et al.
Publicado: (2021)

Silencing of MUC20 suppresses the malignant character of pancreatic ductal adenocarcinoma cells through inhibition of the HGF/MET pathway
por: Chen, Syue-Ting, et al.
Publicado: (2018)

Emergence of HGF/SF-Induced Coordinated Cellular Motility
por: Zaritsky, Assaf, et al.
Publicado: (2012)

Elevated Circulating and Placental SPINT2 Is Associated with Placental Dysfunction
por: Murphy, Ciara N., et al.
Publicado: (2021)

Expression of the c-Met/HGF receptor in human melanocytic neoplasms: demonstration of the relationship to malignant melanoma tumour progression.
por: Natali, P. G., et al.
Publicado: (1993)

Simultaneous Inhibition of the HGF/MET and Erk1/2 Pathways Affect Uveal Melanoma Cell Growth and Migration
por: Chattopadhyay, Chandrani, et al.
Publicado: (2014)

Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling
por: Owusu, Benjamin Y., et al.
Publicado: (2016)

HGF/c-Met related activation of β-catenin in hepatoblastoma
por: Purcell, Rachel, et al.
Publicado: (2011)

Expression of HGF and c-Met Proteins in Human Keratoconus Corneas
por: You, Jingjing, et al.
Publicado: (2015)

Activated HGF-c-Met Axis in Head and Neck Cancer
por: Arnold, Levi, et al.
Publicado: (2017)

HGF/c-MET Axis in Tumor Microenvironment and Metastasis Formation
por: Spina, Anna, et al.
Publicado: (2015)

HGF/Met Signaling in Cancer Invasion: The Impact on Cytoskeleton Remodeling
por: Xiang, Chuan, et al.
Publicado: (2017)

HGF/c-Met: A Key Promoter in Liver Regeneration
por: Zhao, Yang, et al.
Publicado: (2022)

RNA-directed epigenetic silencing of Periostin inhibits cell motility
por: Lister, Nicholas C., et al.
Publicado: (2015)

Retraction Note to: Epigenetic regulation of HGF/Met receptor axis is critical for the outgrowth of bone metastasis from breast carcinoma
por: Bendinelli, Paola, et al.
Publicado: (2022)

Dimer Interface in Natural Variant NK1 Is Dispensable for HGF-Dependent Met Receptor Activation
por: Tahira, Yumiko, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6dgrnkc2f3itntq9a8qu9b2b6s