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Abnormal modulation of reward versus punishment learning by a dopamine D2-receptor antagonist in pathological gamblers

RATIONALE: Pathological gambling has been associated with dopamine transmission abnormalities, in particular dopamine D2-receptor deficiency, and reversal learning deficits. Moreover, pervasive theoretical accounts suggest a key role for dopamine in reversal learning. However, there is no empirical...

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Detalles Bibliográficos
Autores principales: Janssen, Lieneke Katharina, Sescousse, Guillaume, Hashemi, Mahur Melina, Timmer, Monique Harmina Maria, ter Huurne, Niels Peter, Geurts, Dirk Everdina Maria, Cools, Roshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537492/
https://www.ncbi.nlm.nih.gov/pubmed/26092311
http://dx.doi.org/10.1007/s00213-015-3986-y