Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α(2)δ-1-induced downregulation of Ca(v)1.2 channels

Availability of voltage-gated calcium channels (Ca(v)) at the plasma membrane is paramount to maintaining the calcium homeostasis of the cell. It is proposed that the ubiquitylation/de-ubiquitylation balance regulates the density of ion channels at the cell surface. Voltage-gated calcium channels Ca...

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Detalles Bibliográficos
Autores principales: Rougier, Jean-Sebastien, Albesa, Maxime, Syam, Ninda, Halet, Guillaume, Abriel, Hugues, Viard, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Ion Channels, Receptors and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537497/
https://www.ncbi.nlm.nih.gov/pubmed/25366495
http://dx.doi.org/10.1007/s00424-014-1636-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537497/
https://www.ncbi.nlm.nih.gov/pubmed/25366495
http://dx.doi.org/10.1007/s00424-014-1636-6

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