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Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α(2)δ-1-induced downregulation of Ca(v)1.2 channels
Availability of voltage-gated calcium channels (Ca(v)) at the plasma membrane is paramount to maintaining the calcium homeostasis of the cell. It is proposed that the ubiquitylation/de-ubiquitylation balance regulates the density of ion channels at the cell surface. Voltage-gated calcium channels Ca...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537497/ https://www.ncbi.nlm.nih.gov/pubmed/25366495 http://dx.doi.org/10.1007/s00424-014-1636-6 |