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How important is randomisation in a stepped wedge trial?

In cluster randomised trials, randomisation increases internal study validity. If enough clusters are randomised, an unadjusted analysis should be unbiased. If a smaller number of clusters are included, stratified or matched randomisation can increase comparability between trial arms. In addition, a...

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Detalles Bibliográficos
Autores principales: Hargreaves, James R, Prost, Audrey, Fielding, Katherine L., Copas, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537545/
https://www.ncbi.nlm.nih.gov/pubmed/26275907
http://dx.doi.org/10.1186/s13063-015-0872-1