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Phylogenetic and amino acid conservation analyses of bacterial l-aspartate-α-decarboxylase and of its zymogen-maturation protein reveal a putative interaction domain

BACKGROUND: All organisms must synthesize the enzymatic cofactor coenzyme A (CoA) from the precursor pantothenate. Most bacteria can synthesize pantothenate de novo by the condensation of pantoate and β-alanine. The synthesis of β-alanine is catalyzed by l-aspartate-α-decarboxylase (PanD), a pyruvoy...

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Detalles Bibliográficos
Autores principales: Stuecker, Tara N, Bramhacharya, Shanti, Hodge-Hanson, Kelsey M, Suen, Garret, Escalante-Semerena, Jorge C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537548/
https://www.ncbi.nlm.nih.gov/pubmed/26276430
http://dx.doi.org/10.1186/s13104-015-1314-6