Models of buffering of dosage imbalances in protein complexes

BACKGROUND: Stoichiometric imbalances in macromolecular complexes can lead to altered function. Such imbalances stem from under- or over-expression of a subunit of a complex consequent to a deletion, duplication or regulatory mutation of an allele encoding the relevant protein. In some cases, the ph...

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Detalles Bibliográficos
Autores principales: Veitia, Reiner A., Birchler, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537584/
https://www.ncbi.nlm.nih.gov/pubmed/26275824
http://dx.doi.org/10.1186/s13062-015-0063-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537584/
https://www.ncbi.nlm.nih.gov/pubmed/26275824
http://dx.doi.org/10.1186/s13062-015-0063-8

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