Inhibition of Epithelial CC-Family Chemokine Synthesis by the Synthetic Chalcone DMPF-1 via Disruption of NF-κB Nuclear Translocation and Suppression of Experimental Asthma in Mice

Asthma is associated with increased pulmonary inflammation and airway hyperresponsiveness. The interaction between airway epithelium and inflammatory mediators plays a key role in the pathogenesis of asthma. In vitro studies evaluated the inhibitory effects of 3-(2,5-dimethoxyphenyl)-1-(5-methylfura...

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Detalles Bibliográficos
Autores principales: Rajajendram, Revathee, Tham, Chau Ling, Akhtar, Mohamad Nadeem, Sulaiman, Mohd Roslan, Israf, Daud Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537758/
https://www.ncbi.nlm.nih.gov/pubmed/26300589
http://dx.doi.org/10.1155/2015/176926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537758/
https://www.ncbi.nlm.nih.gov/pubmed/26300589
http://dx.doi.org/10.1155/2015/176926

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