Cargando…
Inhibition of Epithelial CC-Family Chemokine Synthesis by the Synthetic Chalcone DMPF-1 via Disruption of NF-κB Nuclear Translocation and Suppression of Experimental Asthma in Mice
Asthma is associated with increased pulmonary inflammation and airway hyperresponsiveness. The interaction between airway epithelium and inflammatory mediators plays a key role in the pathogenesis of asthma. In vitro studies evaluated the inhibitory effects of 3-(2,5-dimethoxyphenyl)-1-(5-methylfura...
Autores principales: | Rajajendram, Revathee, Tham, Chau Ling, Akhtar, Mohamad Nadeem, Sulaiman, Mohd Roslan, Israf, Daud Ahmad |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537758/ https://www.ncbi.nlm.nih.gov/pubmed/26300589 http://dx.doi.org/10.1155/2015/176926 |
Ejemplares similares
-
Evaluation of Antinociceptive Profile of Chalcone Derivative (3-(2,5-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one (DMPF-1) in vivo
por: Abu Bakar, Noor Azlina, et al.
Publicado: (2020) -
Peripheral Antinociception of a Chalcone, Flavokawin B and Possible Involvement of the Nitric Oxide/Cyclic Guanosine Monophosphate/Potassium Channels Pathway
por: Kamaldin, Mohd Nasier, et al.
Publicado: (2013) -
The Protective Effects of a Synthetic Geranyl Acetophenone in a Cellular Model of TNF-α-Induced Pulmonary Epithelial Barrier Dysfunction
por: Sim, Tee Yee, et al.
Publicado: (2018) -
Crosstalk Between Signaling Pathways Involved in the Regulation of Airway Smooth Muscle Cell Hyperplasia
por: Yap, Hui Min, et al.
Publicado: (2019) -
Possible Participation of Ionotropic Glutamate Receptors and l-Arginine-Nitric Oxide-Cyclic Guanosine Monophosphate-ATP-Sensitive K(+) Channel Pathway in the Antinociceptive Activity of Cardamonin in Acute Pain Animal Models
por: Pui Ping, Chung, et al.
Publicado: (2020)