Bleomycin-Treated Chimeric Thy1-Deficient Mice with Thy1-Deficient Myofibroblasts and Thy-Positive Lymphocytes Resolve Inflammation without Affecting the Fibrotic Response

Lung fibrosis is characterized by abnormal accumulation of fibroblasts in the interstitium of the alveolar space. Two populations of myofibroblasts, distinguished by Thy1 expression, are detected in human and murine lungs. Accumulation of Thy1-negative (Thy1(−)) myofibroblasts was shown in the lungs...

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Detalles Bibliográficos
Autores principales: Cohen, Pazit Y., Breuer, Raphael, Zisman, Philip, Wallach-Dayan, Shulamit B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537759/
https://www.ncbi.nlm.nih.gov/pubmed/26300593
http://dx.doi.org/10.1155/2015/942179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537759/
https://www.ncbi.nlm.nih.gov/pubmed/26300593
http://dx.doi.org/10.1155/2015/942179

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