SDF-1/CXCR4 Axis Promotes MSCs to Repair Liver Injury Partially through Trans-Differentiation and Fusion with Hepatocytes

MSCs have become a popular target for developing end-stage liver therapies. In this study, two models of bone marrow chimeric mice were used to construct the liver failure models. Then it was found that MSCs can transdifferentiate into hepatocyte-like cells and these hepatocyte-like cells can signif...

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Detalles Bibliográficos
Autores principales: Hao, Ning-Bo, Li, Chang-Zhu, Lü, Mu-Han, Tang, Bo, Wang, Su-Min, Wu, Yu-Yun, Liang, Guang-Ping, Yang, Shi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537768/
https://www.ncbi.nlm.nih.gov/pubmed/26300925
http://dx.doi.org/10.1155/2015/960387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537768/
https://www.ncbi.nlm.nih.gov/pubmed/26300925
http://dx.doi.org/10.1155/2015/960387

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