Exome sequencing followed by genotyping suggests SYPL2 as a susceptibility gene for morbid obesity

Recently developed high-throughput sequencing technology shows power to detect low-frequency disease-causing variants by deep sequencing of all known exons. We used exome sequencing to identify variants associated with morbid obesity. DNA from 100 morbidly obese adult subjects and 100 controls were...

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Detalles Bibliográficos
Autores principales: Jiao, Hong, Arner, Peter, Gerdhem, Paul, Strawbridge, Rona J, Näslund, Erik, Thorell, Anders, Hamsten, Anders, Kere, Juha, Dahlman, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538196/
https://www.ncbi.nlm.nih.gov/pubmed/25406998
http://dx.doi.org/10.1038/ejhg.2014.255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538196/
https://www.ncbi.nlm.nih.gov/pubmed/25406998
http://dx.doi.org/10.1038/ejhg.2014.255

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