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The reversal of pulmonary vascular remodeling through inhibition of p38 MAPK-alpha: a potential novel anti-inflammatory strategy in pulmonary hypertension

The p38 mitogen-activated protein kinase (MAPK) system is increasingly recognized as an important inflammatory pathway in systemic vascular disease but its role in pulmonary vascular disease is unclear. Previous in vitro studies suggest p38 MAPKα is critical in the proliferation of pulmonary artery...

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Detalles Bibliográficos
Autores principales: Church, Alistair C., Martin, Damien H., Wadsworth, Roger, Bryson, Gareth, Fisher, Andrew J., Welsh, David J., Peacock, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538235/
https://www.ncbi.nlm.nih.gov/pubmed/26024891
http://dx.doi.org/10.1152/ajplung.00038.2015