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The reversal of pulmonary vascular remodeling through inhibition of p38 MAPK-alpha: a potential novel anti-inflammatory strategy in pulmonary hypertension
The p38 mitogen-activated protein kinase (MAPK) system is increasingly recognized as an important inflammatory pathway in systemic vascular disease but its role in pulmonary vascular disease is unclear. Previous in vitro studies suggest p38 MAPKα is critical in the proliferation of pulmonary artery...
Autores principales: | Church, Alistair C., Martin, Damien H., Wadsworth, Roger, Bryson, Gareth, Fisher, Andrew J., Welsh, David J., Peacock, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538235/ https://www.ncbi.nlm.nih.gov/pubmed/26024891 http://dx.doi.org/10.1152/ajplung.00038.2015 |
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