Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells

Cell lines have been used for drug discovery as useful models of cancers; however, they do not recapitulate cancers faithfully, especially in the points of rapid growth rate and microenvironment independency. Consequently, the majority of conventional anti-cancer drugs are less sensitive to slow gro...

Descripción completa

Detalles Bibliográficos
Autores principales: Sugimoto, Keiki, Hayakawa, Fumihiko, Shimada, Satoko, Morishita, Takanobu, Shimada, Kazuyuki, Katakai, Tomoya, Tomita, Akihiro, Kiyoi, Hitoshi, Naoe, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538400/
https://www.ncbi.nlm.nih.gov/pubmed/26278963
http://dx.doi.org/10.1038/srep13054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538400/
https://www.ncbi.nlm.nih.gov/pubmed/26278963
http://dx.doi.org/10.1038/srep13054

Ejemplares similares