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Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells
Cell lines have been used for drug discovery as useful models of cancers; however, they do not recapitulate cancers faithfully, especially in the points of rapid growth rate and microenvironment independency. Consequently, the majority of conventional anti-cancer drugs are less sensitive to slow gro...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538400/ https://www.ncbi.nlm.nih.gov/pubmed/26278963 http://dx.doi.org/10.1038/srep13054 |