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Influenza A(H7N9) Virus Acquires Resistance-Related Neuraminidase I222T Substitution When Infected Mallards Are Exposed to Low Levels of Oseltamivir in Water

Influenza A virus (IAV) has its natural reservoir in wild waterfowl, and new human IAVs often contain gene segments originating from avian IAVs. Treatment options for severe human influenza are principally restricted to neuraminidase inhibitors (NAIs), among which oseltamivir is stockpiled in prepar...

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Detalles Bibliográficos
Autores principales: Gillman, Anna, Nykvist, Marie, Muradrasoli, Shaman, Söderström, Hanna, Wille, Michelle, Daggfeldt, Annika, Bröjer, Caroline, Waldenström, Jonas, Olsen, Björn, Järhult, Josef D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538561/
https://www.ncbi.nlm.nih.gov/pubmed/26077257
http://dx.doi.org/10.1128/AAC.00886-15