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Variants in the Regulatory Region of WNT5A Reduced Risk of Cardiac Conotruncal Malformations in the Chinese Population

WNT5A is one of the most highly investigated non-canonical Wnt ligands and is involved in the embryonic heart development, especially in formation of the cardiac conotruncal region by regulating the migration and differentiation of cardiac neural crest (CNC) and second heart field (SHF) cells. No st...

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Detalles Bibliográficos
Autores principales: Li, Peiqiang, Li, Haijie, Zheng, Yufang, Qiao, Bin, Duan, Wenyuan, Huang, Lijuan, Liu, Weiqi, Wang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538571/
https://www.ncbi.nlm.nih.gov/pubmed/26278011
http://dx.doi.org/10.1038/srep13120