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Triptycene-based small molecules modulate (CAG)·(CTG) repeat junctions

Nucleic acid three-way junctions (3WJs) play key roles in biological processes such as nucleic acid replication in addition to being implicated as dynamic transient intermediates in trinucleotide repeat sequences. Structural modulation of specific nucleic acid junctions could allow for control of bi...

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Detalles Bibliográficos
Autores principales: Barros, Stephanie A., Chenoweth, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538686/
https://www.ncbi.nlm.nih.gov/pubmed/26366282
http://dx.doi.org/10.1039/c5sc01595b