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Triptycene-based small molecules modulate (CAG)·(CTG) repeat junctions
Nucleic acid three-way junctions (3WJs) play key roles in biological processes such as nucleic acid replication in addition to being implicated as dynamic transient intermediates in trinucleotide repeat sequences. Structural modulation of specific nucleic acid junctions could allow for control of bi...
Autores principales: | Barros, Stephanie A., Chenoweth, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538686/ https://www.ncbi.nlm.nih.gov/pubmed/26366282 http://dx.doi.org/10.1039/c5sc01595b |
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