A Short N-terminal Domain of HDAC4 Preserves Photoreceptors and Restores Visual Function in Retinitis Pigmentosa

Retinitis pigmentosa is a leading cause of inherited blindness, with no effective treatment currently available. Mutations primarily in genes expressed in rod photoreceptors lead to early rod death, followed by a slower phase of cone photoreceptor death. Rd1 mice provide an invaluable animal model t...

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Detalles Bibliográficos
Autores principales: Guo, Xinzheng, Wang, Shao-Bin, Xu, Hongping, Ribic, Adema, Mohns, Ethan J., Zhou, Yu, Zhu, Xianjun, Biederer, Thomas, Crair, Michael C., Chen, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538705/
https://www.ncbi.nlm.nih.gov/pubmed/26272629
http://dx.doi.org/10.1038/ncomms9005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538705/
https://www.ncbi.nlm.nih.gov/pubmed/26272629
http://dx.doi.org/10.1038/ncomms9005

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