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Improving small RNA-seq by using a synthetic spike-in set for size-range quality control together with a set for data normalization

There is an increasing interest in complementing RNA-seq experiments with small-RNA (sRNA) expression data to obtain a comprehensive view of a transcriptome. Currently, two main experimental challenges concerning sRNA-seq exist: how to check the size distribution of isolated sRNAs, given the sensiti...

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Detalles Bibliográficos
Autores principales: Locati, Mauro D., Terpstra, Inez, de Leeuw, Wim C., Kuzak, Mateusz, Rauwerda, Han, Ensink, Wim A., van Leeuwen, Selina, Nehrdich, Ulrike, Spaink, Herman P., Jonker, Martijs J., Breit, Timo M., Dekker, Rob J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538800/
https://www.ncbi.nlm.nih.gov/pubmed/25870415
http://dx.doi.org/10.1093/nar/gkv303