Single-cell, locus-specific bisulfite sequencing (SLBS) for direct detection of epimutations in DNA methylation patterns

Stochastic epigenetic changes drive biological processes, such as development, aging and disease. Yet, epigenetic information is typically collected from millions of cells, thereby precluding a more precise understanding of cell-to-cell variability and the pathogenic history of epimutations. Here we...

Descripción completa

Detalles Bibliográficos
Autores principales: Gravina, Silvia, Ganapathi, Shireen, Vijg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538804/
https://www.ncbi.nlm.nih.gov/pubmed/25897117
http://dx.doi.org/10.1093/nar/gkv366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538804/
https://www.ncbi.nlm.nih.gov/pubmed/25897117
http://dx.doi.org/10.1093/nar/gkv366

Ejemplares similares