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Dissecting the nascent human transcriptome by analysing the RNA content of transcription factories

While mapping total and poly-adenylated human transcriptomes has now become routine, characterizing nascent transcripts remains challenging, largely because nascent RNAs have such short half-lives. Here, we describe a simple, fast and cost-effective method to isolate RNA associated with transcriptio...

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Detalles Bibliográficos
Autores principales: Caudron-Herger, Maïwen, Cook, Peter R., Rippe, Karsten, Papantonis, Argyris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538806/
https://www.ncbi.nlm.nih.gov/pubmed/25897132
http://dx.doi.org/10.1093/nar/gkv390