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A predictive biophysical model of translational coupling to coordinate and control protein expression in bacterial operons
Natural and engineered genetic systems require the coordinated expression of proteins. In bacteria, translational coupling provides a genetically encoded mechanism to control expression level ratios within multi-cistronic operons. We have developed a sequence-to-function biophysical model of transla...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538824/ https://www.ncbi.nlm.nih.gov/pubmed/26117546 http://dx.doi.org/10.1093/nar/gkv635 |