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Site-specific labeling of RNA by combining genetic alphabet expansion transcription and copper-free click chemistry

Site-specific labeling of long-chain RNAs with desired molecular probes is an imperative technique to facilitate studies of functional RNA molecules. By genetic alphabet expansion using an artificial third base pair, called an unnatural base pair, we present a post-transcriptional modification metho...

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Detalles Bibliográficos
Autores principales: Someya, Tatsuhiko, Ando, Ami, Kimoto, Michiko, Hirao, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538826/
https://www.ncbi.nlm.nih.gov/pubmed/26130718
http://dx.doi.org/10.1093/nar/gkv638