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Structures of the T. brucei kRNA editing factor MRB1590 reveal unique RNA-binding pore motif contained within an ABC-ATPase fold

Kinetoplastid RNA (kRNA) editing is a process that creates translatable mitochondrial mRNA transcripts from cryptogene encoded RNAs and is unique for kinetoplastids, such as Trypanosoma brucei. In addition to the catalytic 20S editosome, multiple accessory proteins are required for this conversion....

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Detalles Bibliográficos
Autores principales: Shaw, Porsha L. R., McAdams, Natalie M., Hast, Michael A., Ammerman, Michelle L., Read, Laurie K., Schumacher, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538832/
https://www.ncbi.nlm.nih.gov/pubmed/26117548
http://dx.doi.org/10.1093/nar/gkv647