Structural basis for substrate recognition and processive cleavage mechanisms of the trimeric exonuclease PhoExo I

Nucleases play important roles in nucleic acid processes, such as replication, repair and recombination. Recently, we identified a novel single-strand specific 3′-5′ exonuclease, PfuExo I, from the hyperthermophilic archaeon Pyrococcus furiosus, which may be involved in the Thermococcales-specific D...

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Detalles Bibliográficos
Autores principales: Miyazono, Ken-ichi, Ishino, Sonoko, Tsutsumi, Kanae, Ito, Tomoko, Ishino, Yoshizumi, Tanokura, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538837/
https://www.ncbi.nlm.nih.gov/pubmed/26138487
http://dx.doi.org/10.1093/nar/gkv654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538837/
https://www.ncbi.nlm.nih.gov/pubmed/26138487
http://dx.doi.org/10.1093/nar/gkv654

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