Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes

During fertilization, an egg and a sperm fuse to form a new embryo. Eggs develop from oocytes in a process called meiosis. Meiosis in human oocytes is highly error-prone(1,2), and defective eggs are the leading cause of pregnancy loss and several genetic disorders such as Down’s syndrome(3-5). Which...

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Detalles Bibliográficos
Autores principales: Pfender, Sybille, Kuznetsov, Vitaliy, Pasternak, Michał, Tischer, Thomas, Santhanam, Balaji, Schuh, Melina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538867/
https://www.ncbi.nlm.nih.gov/pubmed/26147080
http://dx.doi.org/10.1038/nature14568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538867/
https://www.ncbi.nlm.nih.gov/pubmed/26147080
http://dx.doi.org/10.1038/nature14568

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