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Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes
During fertilization, an egg and a sperm fuse to form a new embryo. Eggs develop from oocytes in a process called meiosis. Meiosis in human oocytes is highly error-prone(1,2), and defective eggs are the leading cause of pregnancy loss and several genetic disorders such as Down’s syndrome(3-5). Which...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538867/ https://www.ncbi.nlm.nih.gov/pubmed/26147080 http://dx.doi.org/10.1038/nature14568 |