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Protein kinase C delta null mice exhibit structural alterations in articular surface, intra-articular and subchondral compartments
INTRODUCTION: Structural alterations in intra-articular and subchondral compartments are hallmarks of osteoarthritis, a degenerative disease that causes pain and disability in the aging population. Protein kinase C delta (PKC-δ) plays versatile functions in cell growth and differentiation, but its r...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538913/ https://www.ncbi.nlm.nih.gov/pubmed/26279273 http://dx.doi.org/10.1186/s13075-015-0720-4 |