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Protein kinase C delta null mice exhibit structural alterations in articular surface, intra-articular and subchondral compartments

INTRODUCTION: Structural alterations in intra-articular and subchondral compartments are hallmarks of osteoarthritis, a degenerative disease that causes pain and disability in the aging population. Protein kinase C delta (PKC-δ) plays versatile functions in cell growth and differentiation, but its r...

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Detalles Bibliográficos
Autores principales: Yang, Xiaohong, Teguh, Dian, Wu, Jian-Ping, He, Bo, Kirk, Thomas Brett, Qin, Shengnan, Li, Siming, Chen, Honghui, Xue, Wei, Ng, Benjamin, Chim, Shek Man, Tickner, Jennifer, Xu, Jiake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538913/
https://www.ncbi.nlm.nih.gov/pubmed/26279273
http://dx.doi.org/10.1186/s13075-015-0720-4