Control of Caenorhabditis elegans germ-line stem-cell cycling speed meets requirements of design to minimize mutation accumulation

BACKGROUND: Stem cells are thought to play a critical role in minimizing the accumulation of mutations, but it is not clear which strategies they follow to fulfill that performance objective. Slow cycling of stem cells provides a simple strategy that can minimize cell pedigree depth and thereby mini...

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Detalles Bibliográficos
Autores principales: Chiang, Michael, Cinquin, Amanda, Paz, Adrian, Meeds, Edward, Price, Christopher A., Welling, Max, Cinquin, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538916/
https://www.ncbi.nlm.nih.gov/pubmed/26187634
http://dx.doi.org/10.1186/s12915-015-0148-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538916/
https://www.ncbi.nlm.nih.gov/pubmed/26187634
http://dx.doi.org/10.1186/s12915-015-0148-y

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