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A polymorphism at the microRNA binding site in the 3′ untranslated region of RYR3 is associated with outcome in hepatocellular carcinoma

OBJECTIVE: MicroRNAs can bind to the 3′ untranslated regions (UTRs) of messenger RNAs, where they interfere with the translation of targeting genes, thereby regulating cell differentiation, apoptosis, and tumorigenesis. In this study, three microRNA binding site single nucleotide polymorphisms (SNPs...

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Detalles Bibliográficos
Autores principales: Peng, Chenxing, Guo, Zhanjun, Wu, Xiaoyan, Zhang, Xiao-lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539090/
https://www.ncbi.nlm.nih.gov/pubmed/26309413
http://dx.doi.org/10.2147/OTT.S85856