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A polymorphism at the microRNA binding site in the 3′ untranslated region of RYR3 is associated with outcome in hepatocellular carcinoma
OBJECTIVE: MicroRNAs can bind to the 3′ untranslated regions (UTRs) of messenger RNAs, where they interfere with the translation of targeting genes, thereby regulating cell differentiation, apoptosis, and tumorigenesis. In this study, three microRNA binding site single nucleotide polymorphisms (SNPs...
Autores principales: | Peng, Chenxing, Guo, Zhanjun, Wu, Xiaoyan, Zhang, Xiao-lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539090/ https://www.ncbi.nlm.nih.gov/pubmed/26309413 http://dx.doi.org/10.2147/OTT.S85856 |
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