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Multifunctional Analysis of CD4(+) T-Cell Response as Immune-Based Model for Tuberculosis Detection

Mono- and multifunctional specific CD4(+) and CD8(+) T-cell responses were evaluated to improve the immune-based detection of active tuberculosis (TB) and latent infection (LTBI). We applied flow cytometry to investigate cytokines profile (IFN-γ, TNF-α, and IL-2) of T cells after stimulation with TB...

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Detalles Bibliográficos
Autores principales: Lichtner, Miriam, Mascia, Claudia, Sauzullo, Ilaria, Mengoni, Fabio, Vita, Serena, Marocco, Raffaella, Belvisi, Valeria, Russo, Gianluca, Vullo, Vincenzo, Mastroianni, Claudio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539126/
https://www.ncbi.nlm.nih.gov/pubmed/26339657
http://dx.doi.org/10.1155/2015/217287