Higher Matrix Stiffness Upregulates Osteopontin Expression in Hepatocellular Carcinoma Cells Mediated by Integrin β1/GSK3β/β-Catenin Signaling Pathway

Increased stromal stiffness is associated with hepatocellular carcinoma (HCC) development and progression. However, the molecular mechanism by which matrix stiffness stimuli modulate HCC progress is largely unknown. In this study, we explored whether matrix stiffness-mediated effects on osteopontin...

Descripción completa

Detalles Bibliográficos
Autores principales: You, Yang, Zheng, Qiongdan, Dong, Yinying, Wang, Yaohui, Zhang, Lan, Xue, Tongchun, Xie, Xiaoying, Hu, Chao, Wang, Zhiming, Chen, Rongxin, Wang, Yanhong, Cui, Jiefeng, Ren, Zhenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539226/
https://www.ncbi.nlm.nih.gov/pubmed/26280346
http://dx.doi.org/10.1371/journal.pone.0134243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539226/
https://www.ncbi.nlm.nih.gov/pubmed/26280346
http://dx.doi.org/10.1371/journal.pone.0134243

Ejemplares similares