Radiation-Induced Glycogen Accumulation Detected by Single Cell Raman Spectroscopy Is Associated with Radioresistance that Can Be Reversed by Metformin

Altered cellular metabolism is a hallmark of tumor cells and contributes to a host of properties associated with resistance to radiotherapy. Detection of radiation-induced biochemical changes can reveal unique metabolic pathways affecting radiosensitivity that may serve as attractive therapeutic tar...

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Detalles Bibliográficos
Autores principales: Matthews, Quinn, Isabelle, Martin, Harder, Samantha J., Smazynski, Julian, Beckham, Wayne, Brolo, Alexandre G., Jirasek, Andrew, Lum, Julian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539228/
https://www.ncbi.nlm.nih.gov/pubmed/26280348
http://dx.doi.org/10.1371/journal.pone.0135356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539228/
https://www.ncbi.nlm.nih.gov/pubmed/26280348
http://dx.doi.org/10.1371/journal.pone.0135356

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