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Genetic overlap between Alzheimer’s disease and Parkinson’s disease at the MAPT locus

We investigated genetic overlap between Alzheimer’s disease (AD) and Parkinson’s disease (PD). Using summary statistics (p-values) from large recent genomewide association studies (GWAS) (total n = 89,904 individuals), we sought to identify single nucleotide polymorphisms (SNPs) associating with bot...

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Detalles Bibliográficos
Autores principales: Desikan, Rahul S., Schork, Andrew J., Wang, Yunpeng, Witoelar, Aree, Sharma, Manu, McEvoy, Linda K., Holland, Dominic, Brewer, James B., Chen, Chi-Hua, Thompson, Wesley K., Harold, Denise, Williams, Julie, Owen, Michael J., O’Donovan, Michael C., Pericak-Vance, Margaret A., Mayeux, Richard, Haines, Jonathan L., Farrer, Lindsay A., Schellenberg, Gerard D., Heutink, Peter, Singleton, Andrew B., Brice, Alexis, Wood, Nicolas W., Hardy, John, Martinez, Maria, Choi, Seung Hoi, DeStefano, Anita, Ikram, M. Arfan, Bis, Joshua C., Smith, Albert, Fitzpatrick, Annette L., Launer, Lenore, van Duijn, Cornelia, Seshadri, Sudha, Ulstein, Ingun Dina, Aarsland, Dag, Fladby, Tormod, Djurovic, Srdjan, Hyman, Bradley T., Snaedal, Jon, Stefansson, Hreinn, Stefansson, Kari, Gasser, Thomas, Andreassen, Ole A., Dale, Anders M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539304/
https://www.ncbi.nlm.nih.gov/pubmed/25687773
http://dx.doi.org/10.1038/mp.2015.6