Alginate as a protease inhibitor in vitro and in a model gut system; selective inhibition of pepsin but not trypsin

Alginates are widely used in the food and medical industries, including as a Gastro-Oesophagul Reflux treatment. This work investigates the inhibitory effects of alginate on the reflux aggressors trypsin and pepsin and the role of alginate-substrate binding, pH and alginate structure on inhibition....

Descripción completa

Detalles Bibliográficos
Autores principales: Chater, Peter Ian, Wilcox, Mathew D., Brownlee, Iain A., Pearson, Jeffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Applied Science Publishers 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539341/
https://www.ncbi.nlm.nih.gov/pubmed/26256170
http://dx.doi.org/10.1016/j.carbpol.2015.05.062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539341/
https://www.ncbi.nlm.nih.gov/pubmed/26256170
http://dx.doi.org/10.1016/j.carbpol.2015.05.062

Ejemplares similares