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Alginate as a protease inhibitor in vitro and in a model gut system; selective inhibition of pepsin but not trypsin
Alginates are widely used in the food and medical industries, including as a Gastro-Oesophagul Reflux treatment. This work investigates the inhibitory effects of alginate on the reflux aggressors trypsin and pepsin and the role of alginate-substrate binding, pH and alginate structure on inhibition....
Autores principales: | Chater, Peter Ian, Wilcox, Mathew D., Brownlee, Iain A., Pearson, Jeffrey P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Applied Science Publishers
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539341/ https://www.ncbi.nlm.nih.gov/pubmed/26256170 http://dx.doi.org/10.1016/j.carbpol.2015.05.062 |
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