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The assembly and characterisation of two structurally distinct cattle MHC class I haplotypes point to the mechanisms driving diversity

In cattle, there are six classical MHC class I genes that are variably present between different haplotypes. Almost all known haplotypes contain between one and three genes, with an allele of Gene 2 present on the vast majority. However, very little is known about the sequence and therefore structur...

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Detalles Bibliográficos
Autores principales: Schwartz, John C., Hammond, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539362/
https://www.ncbi.nlm.nih.gov/pubmed/26227296
http://dx.doi.org/10.1007/s00251-015-0859-9