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Comparison of single and combination diuretics on glucose tolerance (PATHWAY-3): protocol for a randomised double-blind trial in patients with essential hypertension

INTRODUCTION: Thiazide diuretics are associated with increased risk of diabetes mellitus. This risk may arise from K(+)-depletion. We hypothesised that a K(+)-sparing diuretic will improve glucose tolerance, and that combination of low-dose thiazide with K(+)-sparing diuretic will improve both blood...

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Detalles Bibliográficos
Autores principales: Brown, Morris J, Williams, Bryan, MacDonald, Thomas M, Caulfield, Mark, Cruickshank, J Kennedy, McInnes, Gordon, Sever, Peter, Webb, David J, Salsbury, Jackie, Morant, Steve, Ford, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539390/
https://www.ncbi.nlm.nih.gov/pubmed/26253567
http://dx.doi.org/10.1136/bmjopen-2015-008086