Clique-Based Clustering of Correlated SNPs in a Gene Can Improve Performance of Gene-Based Multi-Bin Linear Combination Test

Gene-based analysis of multiple single nucleotide polymorphisms (SNPs) in a gene region is an alternative to single SNP analysis. The multi-bin linear combination test (MLC) proposed in previous studies utilizes the correlation among SNPs within a gene to construct a gene-based global test. SNPs are...

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Detalles Bibliográficos
Autores principales: Yoo, Yun Joo, Kim, Sun Ah, Bull, Shelley B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539439/
https://www.ncbi.nlm.nih.gov/pubmed/26346579
http://dx.doi.org/10.1155/2015/852341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539439/
https://www.ncbi.nlm.nih.gov/pubmed/26346579
http://dx.doi.org/10.1155/2015/852341

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